Neverness to Everness has no shortage of support options, but Iroi stands apart. She is an S-rank unit whose healing scales directly off ATK%, which means building her correctly turns her into one of the most self-sufficient supports in the game. She fits into most team compositions without requiring heavy investment in her signature Arc, which is rare for a unit at her tier. If you just pulled her and want to get the most out of her kit, this guide covers everything: her best Arc, Cartridge, module stats, and top team options.
What is the best Iroi build in NTE?
Iroi's entire kit revolves around ATK scaling. Her outgoing healing increases with ATK%, so stacking that stat is the single most important thing you can do when building her. Flat ATK fills in the gaps after you have hit a solid ATK% baseline. DMG% and Crit round out the priority list but are secondary concerns.
Best Arc for Iroi
The Wrong Gate is Iroi's signature Arc and the clear best-in-slot option. It boosts her ATK significantly while also increasing allies' damage output, giving it dual value that most Arcs simply do not offer. The good news is that Iroi does not collapse without it. Several alternatives work well enough that you do not need to chase the signature if resources are tight.
If you want to push her healing output higher, Call of the Twisted City is the alternative worth considering. For general ATK-focused builds, Youthful Fantasy, Clear Skies, and Shiny Days all perform at a similar level.

Iroi S-rank support profile
Best Cartridge for Iroi
Speedy Hedgehog is the only real answer here. It grants 12% Charge Efficiency and boosts all allies' ATK by 15% after Iroi uses her Ultimate. That combination of personal efficiency and team-wide ATK amplification is exactly what a support unit needs. No other Cartridge comes close to matching that value for her kit.
For sub stats on the Cartridge, target ATK% first. If you find yourself wanting more raw healing output, Healing Bonus is a valid secondary priority.

Speedy Hedgehog Cartridge stats
What are the best teams for Iroi?
Iroi's flexibility is her biggest selling point. She slots into most team compositions as a support, and she outperforms both Haniel and Sakiri in several key matchups. Her best team places her alongside Shinku, Hathor, and Esper Zero, where she functions as the primary support for Shinku's damage output.
The Shinku composition is her strongest home. Iroi's ATK buffs and healing keep Shinku in the fight while Hathor and Esper Zero handle sub-DPS and utility duties.
In Nanally teams, Iroi replaces Sakiri and provides a comparable support profile. If you are running a Nanally build and do not have Sakiri, Iroi is a direct upgrade.
For Chaos teams, Iroi steps in where Haniel would normally sit. The ATK amplification from Speedy Hedgehog pairs well with Chaos's damage scaling. Check the full Chaos build guide if you want to optimize that composition further.

Iroi's best team setup
Module layout and stat priorities
Once the Cartridge is locked in, the module layout determines how much of Iroi's potential you actually unlock. The priority is straightforward: ATK% in every slot you can manage, with flat ATK filling any remaining gaps. DMG% and Crit come after those two are covered.
For the Type III bonus module, always select Anima DMG Bonus. Even though Iroi is not a carry, the additional damage contributes to her overall kit and should not be ignored.
Building Iroi this way places her comfortably at the top of the NTE support tier. For a full picture of where she stacks up against every other character in the game, the NTE character tier list has a complete breakdown.
Final thoughts on the Iroi build
Iroi is one of the easier S-rank units to build well because her stat priorities are clean and her best Cartridge has no real competition. The Wrong Gate is her ideal Arc, but she remains strong with several alternatives, which takes a lot of pressure off the gacha. Stack ATK%, run Speedy Hedgehog, and slot her into a Shinku or Nanally team and she will carry her weight every fight.
For more builds, team comps, and strategy across every character in the game, the full Neverness to Everness guide collection has everything you need to stay ahead of the meta.


